Acetyl octapeptide-3, cosmetic peptide

SNAP-8

SNAP-25

SNAP-8 is acetyl octapeptide-3, a topical cosmetic peptide designed around SNAP-25-related neurotransmitter release. Comparisons with botulinum toxin are mainly mechanistic; penetration through intact skin and clinical effect size are poorly studied.

1Overview
-Reference frequency
DataIn vitro and limited cosmetic research
Research status

Cosmetic ingredient; not an injection product

Velora SNAP-8 vial
SNAP-810 MG
01 · Overview

What is SNAP-8?

SNAP-8 is acetyl octapeptide-3, a topical cosmetic peptide designed around SNAP-25-related neurotransmitter release. Comparisons with botulinum toxin are mainly mechanistic; penetration through intact skin and clinical effect size are poorly studied.

Research route, formulation and population determine what a result actually means.

01

SNAP-25

SNAP-8 was designed around SNAP-25-related neurotransmitter release and studied topically.

02 · Research

What do the studies show?

In vitro and limited cosmetic research. Educational information. Not diagnosis, treatment or use advice.

Topical
Limited evidence

Cosmetic formulations

Small comparative studies report changes in wrinkle measures, often using multi-ingredient products and without strong independent replication.

03 · DATA

Peptide and product specifications

Checked identity data for this research compound or blend.

SNAP-8Peptide and product specifications
Product type
Topical cosmetic octapeptide; not an injectable dosing product
Molecular formula
C₄₂H₇₂N₁₆O₁₅S
Molecular weight
1073.2 g/mol
CAS number
868844-74-0
Amino-acid sequence / components
Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH₂
Amino-acid count
8
Purity
Batch-specific - confirm identity and purity with the Velora COA
Reference diluent
Only according to a validated topical formulation
Unreconstituted-material storage
Follow the accompanying COA, product label and validated stability data

These are compound references, not a batch certificate. Purity and identity of a specific Velora batch must be confirmed by its accompanying COA and laboratory report.

U.S. EPA CompTox identity record ↗
04 · Calculator

Topical mixing calculator

Not intended for an injection calculator. This module only converts concentration and volume. Inputs are not recommendations or individual dosing advice.

Topical mixing calculator

Topical according to formulation; no injection frequency

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Concentration-
Solution strength-
05 · Safety and limitations

Safety and limitations

Research route, formulation and population determine what a result actually means.

What is known

  • Visible research claims use primary or official sources.
  • The calculator is arithmetic and does not turn a study amount into medical advice.
  • A registered medicine and a research vial are not automatically equivalent.

What remains uncertain

  • Many products lack long-term safety data and independent replication.
  • Animal and cell findings do not predict a safe human dose.
  • Stability depends on formulation, pH, sterility, light, temperature and packaging.
Status: Cosmetic ingredient; not an injection product. Educational information. Not diagnosis, treatment or use advice.
06 · FAQ

Frequently asked questions

SNAP-8 is acetyl octapeptide-3, a topical cosmetic peptide designed around SNAP-25-related neurotransmitter release. Comparisons with botulinum toxin are mainly mechanistic; penetration through intact skin and clinical effect size are poorly studied.
Small comparative studies report changes in wrinkle measures, often using multi-ingredient products and without strong independent replication. Peptides cross the stratum corneum poorly; formulation and delivery system determine exposure.
No. It performs arithmetic conversions only. Medical decisions belong with a licensed healthcare professional.
No product-specific stability curve
2–8 °C. Protect from light and repeated freeze-thaw cycles.
07 · Sources

Primary research sources

Educational information. Not diagnosis, treatment or use advice.

Clinical assessment of an anti-wrinkle product containing acetyl octapeptide-3 Annals of Dermatology, 2024. Link
Topical peptide skin penetration research International Journal of Cosmetic Science, 2015. Link