Copper-binding tripeptide

GHK-Cu

GHK-Cu · Repair

GHK-Cu is a naturally occurring copper complex of glycine-histidine-lysine. Research focuses on extracellular matrix, wound repair and skin biology; evidence for systemic injectable use is far more limited than for topical formulations.

2Overview
1× / dayReference frequency
DataCell, animal and limited topical research
Research status

Cosmetic ingredient; injectable claims not established

Velora GHK-Cu vial
GHK-CU50 MG
01 · Overview

What is GHK-Cu?

GHK-Cu is a naturally occurring copper complex of glycine-histidine-lysine. Research focuses on extracellular matrix, wound repair and skin biology; evidence for systemic injectable use is far more limited than for topical formulations.

Research route, formulation and population determine what a result actually means.

01

GHK-Cu

GHK binds copper and affects signalling associated with skin matrix and repair.

02

Repair

Studies cell migration, vessel formation and matrix repair in wound models.

02 · Research

What do the studies show?

Cell, animal and limited topical research. Educational information. Not diagnosis, treatment or use advice.

03 · DATA

Peptide and product specifications

Checked identity data for this research compound or blend.

GHK-CuPeptide and product specifications
Product type
Copper complex of the tripeptide Gly-His-Lys
Molecular formula
C₁₄H₂₂CuN₆O₄
Molecular weight
401.91 g/mol
CAS number
89030-95-5
Amino-acid sequence / components
Gly-His-Lys (Cu²⁺-complex)
Amino-acid count
3
Purity
Batch-specific — confirm identity and purity with the Velora COA
Reference diluent
Formulation- and batch-specific; there is no universal diluent for every research compound
Unreconstituted-material storage
Follow the accompanying COA, product label and validated stability data

These are compound references, not a batch certificate. Purity and identity of a specific Velora batch must be confirmed by its accompanying COA and laboratory report.

FDA Global Substance Registration System ↗
04 · Calculator

Reconstitution and U-100 conversion

This module only converts concentration and volume. Inputs are not recommendations or individual dosing advice.

Calculator

Once daily in educational protocols

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GHK-Cu vial
GHK-CU
50 MG
Concentration
Per unit
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Calculated duration
LAB · RECONSTITUTION

How to reconstitute GHK-Cu for laboratory research

A visual workflow for controlled laboratory reconstitution. Always follow the product label, COA and a validated protocol.

Five visual laboratory reconstitution steps: clean, measure diluent, add slowly, swirl gently and store according to protocol.
1

Clean

Disinfect the rubber closures of both vials and allow them to dry.

2

Measure diluent

Withdraw only the diluent validated for the specific compound.

3

Add slowly

Let the liquid run slowly down the inside wall of the vial.

4

Swirl gently

Do not shake; rotate gently until the material has dissolved.

5

Store per protocol

Follow the product label, COA and validated stability data.

Important checks before and after reconstitution

Check the product

First confirm that the product is a lyophilised vial. Prefilled pens and ready-to-use solutions do not require reconstitution. Check the label, COA and specified diluent.

Use clean, sterile technique

Wash your hands, clean the work surface and use new sterile equipment for every procedure. Clean both rubber closures with separate alcohol swabs and let them dry completely.

Concentration, not total amount

The volume of liquid added changes the concentration in mg per mL, but not the total amount of research compound in the vial. Use the calculator to check this in advance.

Inspect and label

Check for unexpected discoloration, cloudiness or visible particles. Record the compound, concentration and reconstitution date. Storage time and temperature are product-specific; a fixed 28-day rule does not apply to every compound.

General reconstitution volumes listed by the source

General examples, not a product-specific protocol. The chosen volume determines concentration; always check the label, COA and calculator.

Vial strengthCommonly listed volume
2 mg1–2 mL
5 mg2–3 mL
6 mg2–3 mL
10 mg2–4 mL
15 mg3–5 mL
20 mg4–8 mL

Practical background source: Free Medical Journals — Complete Step-by-Step Guide to Peptide Reconstitution, accessed July 2026. This is a secondary educational source; the product label, COA and validated stability data remain authoritative.

05 · Safety and limitations

Safety and limitations

Research route, formulation and population determine what a result actually means.

What is known

  • Visible research claims use primary or official sources.
  • The calculator is arithmetic and does not turn a study amount into medical advice.
  • A registered medicine and a research vial are not automatically equivalent.

What remains uncertain

  • Many products lack long-term safety data and independent replication.
  • Animal and cell findings do not predict a safe human dose.
  • Stability depends on formulation, pH, sterility, light, temperature and packaging.
Status: Cosmetic ingredient; injectable claims not established. Educational information. Not diagnosis, treatment or use advice.
06 · FAQ

Frequently asked questions

GHK-Cu is a naturally occurring copper complex of glycine-histidine-lysine. Research focuses on extracellular matrix, wound repair and skin biology; evidence for systemic injectable use is far more limited than for topical formulations.
Small studies and preclinical models suggest effects on matrix remodelling, but formulations and endpoints vary widely. Topical or animal data cannot be used to predict a systemic dose or efficacy.
No. It performs arithmetic conversions only. Medical decisions belong with a licensed healthcare professional.
The curve follows the agreed storage model and is not a laboratory result.
2–8 °C. Protect from light and repeated freeze-thaw cycles.
07 · Sources

Primary research sources

Educational information. Not diagnosis, treatment or use advice.

The human tripeptide GHK-Cu in tissue remodelling and gene expression International Journal of Molecular Sciences, 2018. Link
Effects of copper tripeptide on healing irradiated tissues Otolaryngology–Head and Neck Surgery, 2012. Link